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    #enterohepatic circulation

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    Scientific illustration for Bile: The Forgotten Key to Detoxification & Hormonal Balance
    Physiology
    16 MIN READ

    Bile: The Forgotten Key to Detoxification & Hormonal Balance

    Bile — the green-yellow fluid synthesised by hepatocytes from cholesterol, conjugated with taurine or glycine, stored in the gallbladder, and secreted into the duodenum in response to fat ingestion — performs far more than the digestion of dietary fats: it is the primary vehicle through which fat-soluble toxins, excess hormones, heavy metals, and pharmaceutical metabolites are excreted from the body, making adequate bile production and flow the non-negotiable foundation of effective hepatic detoxification. Insufficient bile production — driven by low dietary fat intake following decades of misguided fat-phobic dietary advice, liver congestion, gallbladder removal (cholecystectomy), or pharmaceutical bile acid sequestrant use — creates a bottleneck in detoxification that allows lipophilic toxins to recirculate through enterohepatic recycling rather than being eliminated. The gallbladder epidemic in the UK, with 70,000 cholecystectomies performed annually, is a predictable consequence of the low-fat, high-carbohydrate dietary paradigm that has dominated NHS nutritional guidance for 40 years.

    #bile#gallbladder