TAGGED RESEARCH

#Psychiatry

3TRANSMISSIONS FOUND

Neuroinflammation: The Biological Root of Mental Illness

Neuroinflammation — the activation of the brain's resident immune cells, the microglia, in response to blood-brain barrier disruption, systemic inflammatory signals, heavy metal accumulation, viral or bacterial insult, or oxidative stress — is now recognised by leading neuroscientists as the primary biological driver of depression, anxiety disorders, bipolar disorder, schizophrenia, and the majority of conditions currently categorised as psychiatric illness. Pro-inflammatory cytokines including IL-1β, IL-6, and TNF-α cross the blood-brain barrier and directly inhibit tryptophan hydroxylase (reducing serotonin synthesis), disrupt dopamine signalling, and impair hippocampal neurogenesis — the biological mechanisms of the mood disorders for which the NHS prescribes SSRIs and antipsychotics without addressing the underlying inflammatory aetiology. This paradigm shift from chemical imbalance to immune-inflammatory models of mental illness has profound and largely unimplemented implications for psychiatry.

#neuroinflammation#microglia

Scientific illustration for Psychobiotics: Engineering Mental Health Through Fermentation

Fermented Foods & Probiotic Medicine

12 MIN READ

Psychobiotics: Engineering Mental Health Through Fermentation

Specific probiotic strains produce neurotransmitters like GABA and serotonin directly in the gut. This emerging field offers a biological alternative to pharmaceutical antidepressants for the British public.

#Psychiatry#Neurotransmitters

Scientific illustration for Microbial Transfusion: Rewiring the Neuro-Endocrine Axis

Faecal Microbiota Transplant (FMT)

9 MIN READ

Microbial Transfusion: Rewiring the Neuro-Endocrine Axis

Exploring the neuro-endocrine implications of FMT, focusing on how microbial diversity regulates systemic inflammation and neurotransmitter precursors.

#Mental Health#Neuroscience

CROSS-REFERENCED TOPICS

#neuroinflammation #microglia #mental health #depression #cytokines #serotonin #brain #Neurotransmitters #Mental Health #Neuroscience #Gut-Brain Axis